cia is a crossword puzzle answer that we have spotted 13 times. Spy org. Spy grp. US spy group (inits) "World Factbook" org. secretive langley org. langley-based organisation equivalent of the sis in the us org. for melissa mccarthy's "spy" character Jack Ryan's org. in "The Hunt for Red October" organisation whose 11th director was george h w bush Employer of Carrie Mathison on "Homeland," for short Government department once headed by George H.W. Bush: Abbr. Its Twitter debut: "We can neither confirm nor deny that this is our first tweet"