Isaac is a crossword puzzle answer that we have spotted 15 times. Writer Asimov Sir .. Newton Esau's father Abraham's son physicist newton Hebrew patriarch Sci-fi writer Asimov The only son of Abraham Father of Jacob and Esau Son of Abraham and Sarah Sir ...... Newton, scientist Chap's tax-free savings account biblical father of esau and jacob Husband of Rebecca in the Old Testament Famous astronomer and physicist, .. Newton